Phenotypes And Genotypes: The Search For Influential Genes (Computational Biology, 18) - 9781447173809

This timely text presents a comprehensive guide to genetic association, a new and rapidly expanding field that aims to elucidate how our genetic code (genotypes) influences the traits we possess (phenotypes). The book provides a detailed review of methods of gene mapping used in association with experimental crosses, as well as genome-wide association studies. Emphasis is placed on model selection procedures for analyzing data from large-scale genome scans based on specifically designed modifications of the Bayesian information criterion. Features: presents a thorough introduction to the theoretical background to studies of genetic association (both genetic and statistical); reviews the latest advances in the field; illustrates the properties of methods for mapping quantitative trait loci using computer simulations and the analysis of real data; discusses open challenges; includes an extensive statistical appendix as a reference for those who are not totally familiar with the fundamentals of statistics.

• | Author: Florian Frommlet|Malgorzata Bogdan|David Ramsey
• | Publisher: Springer
• | Publication Date: Mar 20, 2019
• | Number of Pages: 234 pages
• | Language: English
• | Binding: Paperback/Computers
• | ISBN-10: 1447173805
• | ISBN-13: 9781447173809