Antibiotics and Antibiotic Resistance in the Environment

The presence of antibiotics, antibiotic resistance genes, and antibiotic resistant bacteria in the environment is a cause of growing worldwide concern, as it reveals the extensive impact of antibiotic abuse and other human-related pressures upon microbes. Also, the potential clinical and environmental impact of the presence of antibiotics and resistance outside the obvious clinical settings is mostly unknown, but could be unexpectedly large; resistance in clinically-relevant organisms and conditions can be seen as a very small "tip of the iceberg". The detection and measuring of resistance in the environment has rapidly evolved, from mostly anecdotal reports at the end of the 1990s, to a systematic search for organisms and genes in a wide variety of settings, from ancient permafrost to migratory birds. This book reviews the available evidence and hypotheses on where this resistance is coming from and for how long it has been there; what are the effects of the continuous release of antibiotics into the environment; what are the selective and maintenance pressures involved, and how is resistance spreading; what are the known and possible traits that are being co-selected and spread along with antibiotic resistance ones; and what are the laboratory and in-silico strategies -and their limitations, to look into this issue. Book jacket.

• | Author: Carlos F. Amabile-Cuevas
• | Publisher: Crc Press
• | Publication Date: Jun 30, 2020
• | Number of Pages: 126 pages
• | Language: English
• | Binding: Paperback
• | ISBN-10: 0367575175
• | ISBN-13: 9780367575175