RNA Therapeutics: The Evolving Landscape of RNA Therapeutics

RNA Therapeutics: The Evolving Landscape of RNA Therapeutics provides a comprehensive overview of RNA therapeutic modalities, from bench-to-bedside, with emphasis on the increasingly impactful areas of gene therapy, oligonucleotide therapeutics, gene editing, and delivery. International leaders in the field examine RNA-based therapeutics tools that have been developed to-date to modulate cellular processes such as transcription, translation, and protein function. Approved RNA-based therapies and lessons learned from failed therapies are discussed in-depth, as are evolving advances in RNA biochemical analysis, and similar advances that are enabling clinical application of RNA-based therapies. Later sections discuss delivery technologies, remaining hurdles in research and translation; the therapy development process from the lab to the clinic; and novel RNA-based therapies currently in development. Features leading experts in the field of RNA therapeutics, spanning all classes of RNA therapies Provides detailed examination of approved RNA therapies and lessons learned from failed therapeutics Covers all aspects of therapeutic discovery and preclinical development, as well as clinical translation, manufacturing, and regulatory aspects

• | Author: Paloma H. Giangrande, Vittorio Defranciscis, John J. Rossi
• | Publisher: Academic Press
• | Publication Date: May 02, 2022
• | Number of Pages: 472 pages
• | Language: English
• | Binding: Paperback
• | ISBN-10: 012821595X
• | ISBN-13: 9780128215951